Statistical Significance of Normalized Global Alignment
نویسندگان
چکیده
منابع مشابه
Statistical Significance of Normalized Global Alignment
The comparison of homologous proteins from different species is a first step toward a function assignment and a reconstruction of the species evolution. Though local alignment is mostly used for this purpose, global alignment is important for constructing multiple alignments or phylogenetic trees. However, statistical significance of global alignments is not completely clear, lacking a specific...
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When assessing map accuracy, confusion matrices are frequently statistically compared using kappa. While kappa allows individual matrix categories to be analyzed with respect to either omission or commission error rates, kappa is not used to compare individual matrix categories with respect to both rates concurrently. When this concurrent comparison is desired, the ma trices are typically norma...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2014
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2012.0167